The Cahulawassee River valley in Northern Georgia is one of the last natural pristine areas of the state, which will soon change with the imminent building of a dam on the river, which in turn will flood much of the surrounding land. As such, four Atlanta city slickers - alpha male Lewis Medlock, generally even-keeled Ed Gentry, slightly condescending Bobby Trippe, and wide-eyed Drew Ballinger - decide to take a multi-day canoe trip on the river, which turns into a trip they'll never forget into the dangerous American back-country.