American G.I.s who trespass on a Hindu ceremony are hunted down by a beautiful woman who has the power to transform herself into a cobra.
While stationed in Asia, six American G.I.'s witness the secret ritual of Lamians (worshipers of women who can change into serpents). When discovered by the cult, the High Lamian Priest vows that "the Cobra Goddess will avenge herself". Once back in the United States, a mysterious woman enters into their lives and accidents begin to happen. The shadow of a cobra is seen just before each death.